Evidence map›Paper›PMID 41114926›Full record

ArticleIrish journal of medical science2025

Validation of the STOP-bang tool and prevalence of undiagnosed obstructive sleep apnoea in an irish tertiary cardiology outpatient setting.

James Mannion, Cian Murray, Wail Binalialsharabi, Norma Caples, Susan Foley, Mark Rogan, Patrick Owens

Abstract readValidation Study
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Article in Irish journal of medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

James MannionCardiology Department, University Hospital Waterford, Waterford, Ireland. jamesm2016@gmail.com.ORCID http://orcid.org/0000-0001-6232-6629
Cian MurrayCardiology Department, St. James's Hospital, Dublin, Ireland.
Wail BinalialsharabiRespiratory Department, University Hospital Waterford, Waterford, Ireland.
Norma CaplesCardiology Department, University Hospital Waterford, Waterford, Ireland.
Susan FoleyRespiratory Department, University Hospital Waterford, Waterford, Ireland.
Mark RoganRespiratory Department, University Hospital Waterford, Waterford, Ireland.
Patrick OwensCardiology Department, University Hospital Waterford, Waterford, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObstructive sleep apnoea (OSA) is prevalent among patients with cardiovascular disease and is associated with adverse outcomes. The STOP-Bang questionnaire is a validated screening tool for OSA.

aimsThis study aimed to estimate prevalence of undiagnosed OSA in a general cardiology outpatient population, and validate the tool by correlating results with sleep studies.

methodsSTOP-Bang analyses were conducted on 250 sequential patients in a general cardiology clinic, with informed consent for sleep studies. 50 patients were selected from for sleep studies.

resultsAmong the 245 eligible participants, 118 (48.1%) were classified as high risk for moderate-severe OSA. Of patients deemed "high-risk" on the questionnaire (score ≥ 3), this score had a sensitivity of 68% and a specificity of 80%, a positive predictive value (PPV) of 77.3% and a negative predictive value (NPV) of 71.4% for detecting moderate to severe OSA (Apnoea Hypoxia Index (AHI) ≥ 15). A STOP-Bang score of ≥ 5 was identified as the optimal cut-off for detecting moderate to severe OSA in this population, providing a favourable balance of high specificity (92.9%) and PPV (88.9%), while maintaining reasonable sensitivity (72.7%). The area under the receiver operating characteristic (ROC) curve for predicting AHI was 0.79 (95% confidence interval [CI] 0.62-0.92).

conclusionsThis study highlights the significant prevalence of undiagnosed OSA within the general cardiology population, emphasising the need for efficient and reliable screening methods. The STOP-Bang questionnaire cut off of ≥ 5 is a useful screening tool with high specificity for OSA. Routine screening of all referrals to cardiology clinics would dramatically reduce the rates of undiagnosed OSA and improve mortality.

Indexed as

Sleep Apnea, ObstructiveAdultAgedCardiovascular DiseasesFemaleHumansIrelandMaleMass ScreeningMiddle AgedOutpatientsPolysomnographyPrevalenceSensitivity and SpecificitySurveys and Questionnaires

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.