ArticleInternational journal of implant dentistry2025
Assessment of the effects of hyperbaric oxygen treatment on new bone formation after sinus lift in a diabetic rabbit model.
Article in International journal of implant dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aims to evaluate the effects of hyperbaric oxygen treatment (HBOT) on new bone formation after sinus lift operation in diabetic rabbits.
methods27 New Zealand White rabbits that were alloxan monohydrate-induced diabetics were divided into four groups following the sinus lift procedure. Hyperbaric oxygen treatment was applied to 14 rabbits in experimental groups (HBOT-1, HBOT-2). Subjects were sacrificed after 4 (HBOT-1, C-1) and 8 (HBOT-2, C-2) weeks. Histomorphometry and immunohistochemistry were used in histopathological evaluation.
resultsThe new bone area in the HBOT-1 group is statistically more significant than the C-1 group (p = 0.002) and the new bone area in the HBOT-2 group is statistically more significant than the C-2 group (p = 0.001). The area intensity and severity of staining with anti-collagen I in HBOT-1 group is statistically significant compared to C-1 group (p = 0.001) and in HBOT-2 group compared to C-2 group (p = 0.001). The area intensity and intensity of staining with anti-BMP-2 in the HBOT-1 group is statistically significant compared to the C-1 group (p = 0.000) and in the HBOT-2 group compared to the C-2 group (p = 0.001). The number of new vessels in HBOT-2 group is statistically significant compared to C-2 group (p = 0.000).
conclusionsHyperbaric oxygen treatment in the long and short term increases new bone formation, and intensity the level of collagen type I, bone morphogenetic protein-2, and the vascular endothelial growth factor level, in the long term. Based on these results, it was concluded that the negative impact of diabetes on new bone formation can be recovered with hyperbaric oxygen treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.