Evidence map›Paper›PMID 41114892›Full record

ReviewJournal of neuro-oncology2025

Using data for novel discoveries in neuro-oncology research.

Mackenzie Price, Christine Ann Pittman Ballard, Kristin A Waite, Quinn T Ostrom, Jill S Barnhnoltz-Sloan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neuro-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mackenzie PriceCentral Brain Tumor Registry of the United States, Hinsdale, IL, USA.
Christine Ann Pittman BallardCentral Brain Tumor Registry of the United States, Hinsdale, IL, USA.
Kristin A WaiteWinship Cancer Institute of Emory University, 1365 Clifton Rd, Bldg C, 4th Floor, Atlanta, GA, 30322, USA.
Quinn T OstromCentral Brain Tumor Registry of the United States, Hinsdale, IL, USA.
Jill S Barnhnoltz-SloanCentral Brain Tumor Registry of the United States, Hinsdale, IL, USA. jillbsloan@emory.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe study of brain and central nervous system (CNS) tumors has generated and relied upon abundant and diverse data. Robust and comprehensive real-world datasets (RWD) are crucial for understanding risk factors, prognostic factors and clinical outcomes of those diagnosed with these tumors. RWD contains clinically-rich data collected in the context of routine delivery of care and includes an array of variables derived from electronic health records. These data can be leveraged to gain further insight into disease states, treatments and outcomes. METHODS/

resultsHere, we provide a brief overview of considerations when picking a dataset to utilize, and we describe various sources of neuro-oncology data including cancer registries, administrative claims, and commercial RWD.

conclusionsFuture work will undoubtably include the integration of artificial intelligence and machine learning for the analysis of RWD and include linkage to imaging and unstructured clinical data. Unfortunately most RWD sources lack histopathology characteristics which emphasizes the need for linkage data elements that will allow for accurate tumor analyses.

Indexed as

Biomedical ResearchBrain NeoplasmsCentral Nervous System NeoplasmsMedical OncologyHumansRegistriesAdministrative claimsCancer registriesReal-world data

Identifiers

PMID41114892

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.