Evidence map›Paper›PMID 41114887›Full record

ArticleExperimental & applied acarology2025

Gene expression of long non-coding RNAs and messenger RNAs in Varroa destructor mites exposed to essential oil of camphor leaves.

Siyi Shen, Meng Li, Tongyu Dong, Kai Xu, Lili Wu, Kang Wang, Defang Niu, Qingsheng Niu, Ting Ji, Zhi Wang and 1 more

Abstract read
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In one paragraph

Article in Experimental & applied acarology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Siyi ShenApicultural Research Institute, College of Animal Science and Technology, Yangzhou University, Yangzhou, 225009, China.
Meng LiApicultural Research Institute, College of Animal Science and Technology, Yangzhou University, Yangzhou, 225009, China.
Tongyu DongApicultural Research Institute, College of Animal Science and Technology, Yangzhou University, Yangzhou, 225009, China.
Kai XuApiculture Science Institute of Jilin Province, Jilin, 132108, China.
Lili WuDazhou Animal Husbandry Technology Promotion Station, Dazhou, 635000, China.
Kang WangApicultural Research Institute, College of Animal Science and Technology, Yangzhou University, Yangzhou, 225009, China.
Defang NiuCollege of Food Science and Technology, Jiangsu Agri-animal Husbandry Vocational College, Taizhou, 225300, China.
Qingsheng NiuApiculture Science Institute of Jilin Province, Jilin, 132108, China.
Ting JiApicultural Research Institute, College of Animal Science and Technology, Yangzhou University, Yangzhou, 225009, China.
Zhi WangApiculture Science Institute of Jilin Province, Jilin, 132108, China.
Zheguang LinApicultural Research Institute, College of Animal Science and Technology, Yangzhou University, Yangzhou, 225009, China. z.lin@yzu.edu.cn.

Funding

Earmarked Fund for Modern Agro-industry Technology Research System CARS-44Excellent Youth Foundation of Jiangsu Province BK20240158National Key Research and Development Program of China 2022YFD1600201National Natural Science Foundation of China 32202743National Natural Science Foundation of China 32272935Science and Technology Development Project of Jilin Province 20200402042NCScience and Technology Innovation Development Project of Jilin City 20230501041
6 · The paper itself

Abstract

Honeybees are critical pollinators for global agriculture but face numerous threats, notably the ubiquitous devastating ectoparasitic mite Varroa destructor. Using acaricides and other chemicals to control mites not only fosters pesticide resistance but also harms honeybees and contaminates their products, thus sparking growing interest in natural alternatives, particularly essential oils (EOs). In this study, the EO extracted from the camphor leaves (Cinnamomum camphora) was used to investigate its effects on V. destructor and the underlying RNA regulatory mechanisms. The results showed that 27 long non-coding RNAs (lncRNAs) and 305 mRNAs were differentially expressed between the camphor EO-treated and control groups. GO enrichment analysis revealed that the biological processes associated with differential lncRNA expression, in EO-exposed or unexposed V. destructor mites, were primarily related to cellular and metabolic processes. Additionally, the lncRNA-targeted mRNAs in V. destructor mites exhibited upregulated ABC transporter expression post EO exposure; mRNAs regulated by the P53 signaling pathway were also upregulated. These results suggest that camphor leaf EO may affect mite biology by triggering immune responses and disrupting the ability of mites to evade or suppress the immune system of the host. This study provides novel insights into how natural EOs control mites in terms of RNA regulatory networks.

Indexed as

CamphorCinnamomum camphoraGene ExpressionOils, VolatileRNA, Long NoncodingRNA, MessengerVarroidaeAnimalsPlant LeavesCamphorOils, VolatileRNA, Long NoncodingRNA, MessengerAcaricideEssential oilHoneybeelncRNAVarroa destructor

Identifiers

PMID41114887

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.