Evidence map›Paper›PMID 41114847›Full record

ReviewOrthopadie (Heidelberg, Germany)2025

[Osteo-anabolic treatment strategies].

Ulla Stumpf, Andreas Kurth

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Orthopadie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ulla StumpfKlinik für Orthopädie und Unfallchirurgie, LMU Klinikum, Campus Innenstadt, LMU München, Ziemssenstraße 5, 80336, München, Deutschland. ulla.stumpf@med.uni-muenchen.de.
Andreas KurthOrthopädische Privatpraxis Dr. Baron & Kollegen, Frankfurt/Main, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Teriparatide and abaloparatide are osteoanabolic agents that promote the formation of new bone by activating the PTH1 receptor, significantly reducing the risk of fractures, particularly vertebral fractures. Romosozumab works by inhibiting sclerostin. To maintain the therapeutic benefit after osteoanabolic therapy, subsequent anti-resorptive therapy is obligatory for all of these agents. Teriparatide is approved for use in men and postmenopausal women at high risk of fracture, as well as for the treatment of glucocorticoid-induced osteoporosis. However, the approval of romosozumab and abaloparatide is currently limited to the treatment of postmenopausal women. The choice of drug should be made on a patient-specific basis, taking into account risk factors, fracture history, and comorbidities. Osteoanabolic drugs are an effective therapeutic strategy for reducing individual fracture risk and treating osteoporosis.

Indexed as

Anabolic AgentsBone Density Conservation AgentsOsteoporosisOsteoporotic FracturesParathyroid Hormone-Related ProteinTeriparatideAntibodies, MonoclonalFemaleHumansMaleabaloparatideAnabolic AgentsAntibodies, MonoclonalBone Density Conservation AgentsParathyroid Hormone-Related ProteinromosozumabTeriparatideAbaloparatideFracture historyOsteoporosisRomosozumabTeriparatide

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.