ArticleJournal of acquired immune deficiency syndromes (1999)2026
Life Instability and Its Effects on Psychosocial Syndemic Problems and HIV-Care Outcomes in People Living With HIV in Care in South Florida.
Article in Journal of acquired immune deficiency syndromes (1999), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundStructural life instability may negatively affect HIV-care outcomes in people living with HIV (PLWH), particularly in South Florida, a US HIV epidemic "hotspot" with high rates of poverty, immigration, and inconsistent health care access.
settingPLWH (N = 241) receiving care at a community clinic in Miami were assessed at 2 points.
methodsSequential mediation regression analyses were used to explore the relationships between additive indices of structural life instability (indicators: unemployment, low educational attainment, incarceration history, history of immigration as an adult, housing instability, and lack of a significant other) and psychosocial syndemic burden (indicators: depression, anxiety, trauma history, interpersonal violence, and substance use), self-reported antiretroviral therapy (ART) adherence, and documented HIV RNA viral load (VL) collected through medical records.
resultsParticipants reported an average of 2.23 indicators of life instability at baseline and 3.05 psychosocial syndemic problems at follow-up. Each additional indicator of life instability at baseline predicted a 0.23 increase in syndemic count at follow-up and each additional psychosocial problem at follow-up was associated with a 1.37 percentage point decrease in self-reported ART adherence covarying for baseline life instability. Self-reported adherence was, in turn, significantly inversely associated with participants' continuous log RNA VL when holding variables constant. Finally, there was a significant indirect effect of baseline structural life instability on log RNA VL at follow-up sequentially through psychosocial syndemic burden and ART adherence.
conclusionsResults suggest a temporal relationship between baseline life instability and psychosocial problems that negatively affects HIV-related care outcomes among PLWH in South Florida.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.