Evidence map›Paper›PMID 41114381›Full record

ArticleJournal of pain research2025

Age and Fibromyalgia as Moderators of the Relationships Between Pain and Loneliness: A Longitudinal Study in Patients with Chronic Pain.

Chih-Hsun Wu, Wei-Han Chou, Hao-Han Yang, Tung Lin, Yi-Hsun Long, Chi-Cheng Yang, Wei-Zen Sun, Chih-Peng Lin

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Article in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Chih-Hsun WuDepartment of Psychology, National Chengchi University, Taipei, Taiwan.ORCID 0000-0003-4613-5915
Wei-Han ChouDepartment of Anesthesiology, National Taiwan University Hospital, Taipei, Taiwan.
Hao-Han YangClinical Psychology Center, National Taiwan University Hospital, Taipei, Taiwan.
Tung LinClinical Psychology Center, National Taiwan University Hospital, Taipei, Taiwan.
Yi-Hsun LongClinical Psychology Center, National Taiwan University Hospital, Taipei, Taiwan.
Chi-Cheng YangDepartment of Psychology, National Chengchi University, Taipei, Taiwan.
Wei-Zen SunDepartment of Anesthesiology, National Taiwan University Hospital, Taipei, Taiwan.
Chih-Peng LinDepartment of Anesthesiology, National Taiwan University Hospital, Taipei, Taiwan.ORCID 0000-0003-2928-3203

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The interwoven relationship between social distress and pain is an emerging topic in pain research. The present study aimed to explore the association between pain intensity and loneliness in patients with chronic pain and to further explore fibromyalgia and age as moderators. Patients and Methods: We recruited adult chronic pain patients from a pain clinic in Taiwan. Pain intensity was evaluated by 0-10 numerical rating scale, and loneliness was evaluated by 3-item UCLA loneliness scale. The participants were evaluated at baseline (T0) and at a 3-month follow-up (T1). Cross-lagged path analysis was performed to examine the temporal relationship between pain intensity and loneliness. Multigroup analysis was conducted to examine the moderating effect by two pain diagnostic groups (fibromyalgia /non-fibromyalgia), and three age groups (younger /middle /old). Results: A total of 292 patients were included at T0, and 175 completed the T1 evaluation. The mean age of the participants was 60.42 ± 13.73, and 109 were females. The mean pain intensity was 6.00 ± 2.64 and mean duration was 96.73 ± 109.93 months. The results demonstrated that pain intensity (T0) can negatively predict loneliness (T1) (β = -0.10, p =0.017), and loneliness (T0) can positively predict higher pain intensity (T1) (β = 0.20, p =0.002) and is moderated by fibromyalgia and age groups. Conclusion: The study found the bi-directional relationships between pain and loneliness. However, the direction of prediction from pain to loneliness was negative. This implies that the hypothetical vicious circle of escalating pain and loneliness may warrant further investigation.

Indexed as

age differencefibromyalgialonelinesssocial pain

Identifiers

PMID41114381
PMCPMC12533495

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.