Evidence map›Paper›PMID 41114379›Full record

ArticleIEEE open journal of ultrasonics, ferroelectrics, and frequency control2025

Double Profile Intersection (DoPIo) Ultrasound With Acoustic Radiation Force Tilting Interrogates Young's Modulus in Transversely Isotropic Media: An In Silico Study.

Sabiq Muhtadi, Keita A Yokoyama, Caterina M Gallippi

Abstract read
In one paragraph

Article in IEEE open journal of ultrasonics, ferroelectrics, and frequency control, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sabiq MuhtadiLampe Joint Department of Biomedical Engineering, University of North Carolina (UNC) at Chapel Hill, Chapel Hill, NC 27599 USA; North Carolina State University (NCSU), Raleigh, NC 27695 USA.ORCID 0000-0003-0497-0808
Keita A YokoyamaLampe Joint Department of Biomedical Engineering, University of North Carolina (UNC) at Chapel Hill, Chapel Hill, NC 27599 USA; North Carolina State University (NCSU), Raleigh, NC 27695 USA.ORCID 0000-0003-4386-8056
Caterina M GallippiLampe Joint Department of Biomedical Engineering, University of North Carolina (UNC) at Chapel Hill, Chapel Hill, NC 27599 USA; North Carolina State University (NCSU), Raleigh, NC 27695 USA.ORCID 0000-0003-0514-177X

Funding

VisR Ultrasound for Noninvasively Monitoring Renal Allograft HealthR01DK107740 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Caterina M Gallippi · 2016 to 2026
$5.2M
VisR Ultrasound for Noninvasively Interrogating Stromal Collagen Organization in Women as a Breast Cancer BiomarkerR01CA281150 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Caterina M Gallippi · 2023 to 2026
$1.9M
NCI NIH HHS R01 CA281150NIDDK NIH HHS R01 DK107740
6 · The paper itself

Abstract

This study evaluates the potential for interrogating the Young's elastic moduli in anisotropic media, including tissue, using Double Profile Intersection (DoPIo) ultrasound. DoPIo is an on-axis acoustic radiation force (ARF)-based elasticity imaging method that quantifies shear elasticity without relying on shear wave propagation. It is hypothesized that by applying a range of ARF excitations that are not perpendicular to the axis of symmetry (AoS) of transversely isotropic (TI) materials and monitoring the resultant variation in DoPIo-measured elasticity versus excitation angle, the Young's elastic modulus may be interrogated in addition to the shear elastic modulus. The hypothesis was tested

Indexed as

anisotropyARFIDoPIoelastographyshear modulustransversely isotropic (TI) materialsYoung’s modulus

Identifiers

PMID41114379
PMCPMC12530116

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.