Evidence map›Paper›PMID 41114365›Full record

ArticleFrontiers in oncology2025

Treatment of benign lesions of the proximal femur in young pediatric patients using adult 3.5 mm proximal humerus locking plates.

Zhiqiang Zhao, Xin Liu, Xianbiao Xie, Changye Zou, Junqiang Yin, Haomiao Li, Jingnan Shen

Abstract read
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhiqiang ZhaoDepartment of Musculoskeletal Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Xin LiuDepartment of Musculoskeletal Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Xianbiao XieDepartment of Musculoskeletal Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Changye ZouDepartment of Musculoskeletal Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Junqiang YinDepartment of Musculoskeletal Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Haomiao LiThird Affiliated Hospital, Southern Medical University, Guangzhou, China.
Jingnan ShenDepartment of Musculoskeletal Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to assess the efficacy of using adult 3.5 mm proximal humerus locking plates (PHLPs) for treating benign proximal femur lesions in skeletally immature pediatric patients. Between 2011 and 2021, 22 skeletally immature pediatric patients were treated with adult 3.5 mm PHLPs for benign lesions of the proximal femur. During this period, indications for the procedure included lesions involving bone cyst (BC), aneurysmal bone cyst (ABC), and fibrous dysplasia (FD) of the proximal femur, resulting in impending or actual pathologic fractures. The mean follow-up time for the entire group of patients (n=22) was 57 months (range, 27-118 months). A visual analog scale (VAS) scoring system was used for patients with pathological fractures to assess postoperative pain relief. Functional outcomes were evaluated using the Musculoskeletal Tumor Society (MSTS) lower extremity scoring system. Postoperatively, the mean total MSTS score (measured at the most recent follow-up) was 29.41 (95% CI, 29.11 to 29.70) for the entire group of patients. The mean pain relief for patients with actual pathological fractures assessed by VAS was 4.88 (95% CI, 4,30 to 5.45). One patient with ABC and two patients with FD experienced recurrences, necessitating a second surgery at 22, 10, and 15 months post-initial surgery, respectively. Following the second surgery, the locking plates in the patients with ABC and one FD case were removed 30 and 12 months after the initial surgery. The third FD patient, who did not have a pathological fracture, retained the locking plate as of the latest follow-up. Only one patient had delayed wound healing after the initial surgery, and the others had no other complications. 18 patients had their locking plates removed at a mean time of 23 months (95% CI, 18 to 28). In conclusion, treatment of benign lesions of the proximal femur in young pediatric patients with adult 3.5 mm PHLPs provides good functional outcomes and radiological results.

Indexed as

benign tumorpathological fracturepediatricproximal femurproximal humerus locking plate (PHLP)

Identifiers

PMID41114365
PMCPMC12531051

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.