Evidence map›Paper›PMID 41114356›Full record

ArticleFrontiers in oncology2025

Development, feasibility and usability of an app for the correct nutrition of children and adolescents with acute lymphoblastic leukemia.

Andrea Zibaldo, Pio Stellato, Gaia Sepe, Diana Fenicia, Armando Scognamiglio, Francesco Zibaldo, Rosanna Parasole, Giuseppe Menna

Abstract read
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andrea Zibaldo *Department of Oncology, Hematology and Cellular Therapy, Santobono-Pausilipon Children's Hospital, Naples, Italy.
Pio Stellato *Department of Oncology, Hematology and Cellular Therapy, Santobono-Pausilipon Children's Hospital, Naples, Italy.
Gaia SepeDepartment of Oncology, Hematology and Cellular Therapy, Santobono-Pausilipon Children's Hospital, Naples, Italy.
Diana FeniciaDepartment of Oncology, Hematology and Cellular Therapy, Santobono-Pausilipon Children's Hospital, Naples, Italy.
Armando ScognamiglioPediatric Dietetics and Clinical Nutrition Unit, Department of Clinical Management Staff, Santobono-Pausilipon Children's Hospital, Naples, Italy.
Francesco ZibaldoSchool of Science, Engineering and Health, University of Naples "Parthenope", Naples, Italy.
Rosanna ParasoleDepartment of Oncology, Hematology and Cellular Therapy, Santobono-Pausilipon Children's Hospital, Naples, Italy.
Giuseppe MennaDepartment of Oncology, Hematology and Cellular Therapy, Santobono-Pausilipon Children's Hospital, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Proper nutrition during cancer treatment is crucial for children and adolescents with acute lymphoblastic leukemia (ALL), as malnutrition can impact treatment tolerance, survival, and quality of life. In ALL specifically, malnutrition at diagnosis has been associated with increased risk of infections, treatment delays, and poorer survival, while maintaining adequate nutritional status can improve treatment tolerance and long-term outcomes. Materials and methods: We developed and tested the "Hematognam" app, which provides caregivers with dietary guidance for children and adolescents undergoing chemotherapy. This study evaluates the app's feasibility and usability among families of children and adolescents with ALL over a three-month period. Results: The app received high satisfaction ratings, which suggests its user-centric design and relevance in managing complex dietary challenges associated with treatment. Discussion: These results align with previous studies demonstrating the potential of digital health tools to enhance treatment compliance and overall well-being in vulnerable populations. By addressing key nutritional challenges faced by children and adolescents with ALL - such as appetite loss, food aversions, gastrointestinal side effects, and food safety concerns - the "Hematognam" app offers a complementary tool to existing dietary counseling, supporting both families and clinicians in daily nutritional management. The development and implementation of the "Hematognam" app proved feasible and effective in addressing the nutritional needs of children and adolescents with ALL during chemotherapy.

Indexed as

acute lymphoblastic leukemiaapp developmentcancerfamily compliancenutritionpediatricsurvey

Identifiers

PMID41114356
PMCPMC12527835

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.