ReviewACS omega2025
It Is Dangerous to Go Alone: Strategies to Optimize PET Biocatalysis and Upcycling through Enzymatic Synergism.
Review in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Current mainstream methods of plastic recycling are inadequate, producing lower-quality polymers, or are cost-inefficient, requiring expensive reagents operating under harsh conditions. Enzymatic biodegradation of poly-(ethylene terephthalate) (PET) plastic was first extensively described in 2005, and several PET degrading enzymes have been identified since then. Recently discovered or developed PET-degrading enzymes are inhibited by the intermediate reaction product, mono-(2-hydroxyethyl) terephthalate (MHET). Therefore, the enzymatic conversion of PET into its original components, terephthalic acid (TPA) and ethylene glycol (EG), is still inefficient. The synergistic cooperation between PET hydrolases and enzymes capable of hydrolyzing released intermediate products can increase reaction efficiency, reduce separation costs, and enable the full recovery of the basic components of PET for their potential conversion into value-added chemicals. This review aims to provide an overview of enzymes capable of degrading intermediate products and potentially solving the heterogeneous product solution problem, their structures and activities, importance, and potential applications in combination with PET hydrolases.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.