ArticleACS omega2025
Development and Evaluation of Indian Mustard Honey-Loaded Fast Dissolving PVA/AG Nanofibers for Enhanced Neuroprotection.
Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mustard honey (MH) is a rich source of polyphenols, which impart antioxidant, antiapoptotic, and cytoprotective activities in neuronal cells. However, its high-dose requirement for delivering pharmaceutical properties, along with challenges faced by dysphagic individuals, necessitates a controlled delivery system for therapeutic applications. In this study, electrospun nanofibers comprising poly-(vinyl alcohol) (PVA) and acacia gum (AG), loaded with varying concentrations of the Indian variety of MH (5-20%), were designed and developed for sublingual administration. The physicochemical properties of PVA/AG/MH nanofibers, including viscosity, conductivity, morphology, and chemical composition, were investigated. Release kinetics analysis showed that MH release followed a non-Fickian mechanism that was best described by the Korsmeyer-Peppas model, and 15% MH-loaded nanofibers achieved an optimal balance between rapid, predictable release and uniform fiber morphology. The antioxidant potential of the nanofibers was assessed using DPPH and ABTS assays, while their neuroprotective effects were evaluated in HT-22 cells subjected to H
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.