ArticleWorld journal of gastrointestinal oncology2025
Multiparametric magnetic resonance imaging-based predictive model for chemotherapy response in colorectal cancer patients with gene mutations.
Article in World journal of gastrointestinal oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Predictive model based on magnetic resonance imaging for chemotherapy response in colorectal cancer: Toward a radiologic biopsy approach.World journal of gastrointestinal oncology · 2026Article
- Molecular mosaic of colorectal cancer: Why one classification system is no longer enough?World journal of gastrointestinal oncology · 2026Article
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Authors and funding
7 authors.
Funding
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Abstract
backgroundPatients harboring gene mutations like
aimTo create a multiparametric MRI-based predictive model for assessing chemotherapy efficacy in colorectal cancer patients with gene mutations.
methodsThis retrospective study was conducted in a tertiary hospital, analyzing 157 colorectal cancer patients with gene mutations treated between August 2022 and December 2023. Based on chemotherapy outcomes, the patients were categorized into favorable (
resultsUnivariate analysis identified that tumor differentiation, T2 signal intensity ratio, tumor-to-anal margin distance, and MRI-detected lymph node metastasis as significantly associated with chemotherapy response (
conclusionWe established and validated a multiparametric MRI-based model for predicting chemotherapy response in colorectal cancer patients with gene mutations. This model holds promise for guiding individualized treatment strategies.
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