Evidence map›Paper›PMID 41113966›Full record

ArticleAmerican journal of cancer research2025

Metabolic stress-induced dysregulation of the Hippo signaling pathway inhibits the occurrence of hepatocarcinoma.

Shengming Zhang, Lixiang Li, Lei Jin, Ziyi Li, Qianqian Tao, Fuhai Zhou, Xingyang Lu, Qi Zhang, Gaobin Hu, Long Huang and 4 more

Abstract read
In one paragraph

Article in American journal of cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Shengming ZhangDepartment of General Surgery, The First Affiliated Hospital of Anhui University of Chinese Medicine Hefei 230031, Anhui, P. R. China.
Lixiang LiDepartment of General Surgery, The First Affiliated Hospital of Anhui University of Chinese Medicine Hefei 230031, Anhui, P. R. China.
Lei JinDepartment of General Surgery, The First Affiliated Hospital of Anhui University of Chinese Medicine Hefei 230031, Anhui, P. R. China.
Ziyi LiDepartment of General Surgery, The First Affiliated Hospital of Anhui University of Chinese Medicine Hefei 230031, Anhui, P. R. China.
Qianqian TaoDepartment of General Surgery, The First Affiliated Hospital of Anhui University of Chinese Medicine Hefei 230031, Anhui, P. R. China.
Fuhai ZhouDepartment of General Surgery, The First Affiliated Hospital of Anhui University of Chinese Medicine Hefei 230031, Anhui, P. R. China.
Xingyang LuDepartment of General Surgery, The First Affiliated Hospital of Anhui University of Chinese Medicine Hefei 230031, Anhui, P. R. China.
Qi ZhangDepartment of General Surgery, The First Affiliated Hospital of Anhui University of Chinese Medicine Hefei 230031, Anhui, P. R. China.
Gaobin HuDepartment of General Surgery, The First Affiliated Hospital of Anhui University of Chinese Medicine Hefei 230031, Anhui, P. R. China.
Long HuangDepartment of General Surgery, The First Affiliated Hospital of Anhui University of Chinese Medicine Hefei 230031, Anhui, P. R. China.
Liangliang ZhangAffiliated Hospital of The Institute of Neurology, Anhui University of Chinese Medicine Hefei 230061, Anhui, P. R. China.
Qiyu FengCancer Research Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China Hefei 230036, Anhui, P. R. China.
Hui PengDepartment of General Surgery, The First Affiliated Hospital of Anhui University of Chinese Medicine Hefei 230031, Anhui, P. R. China.
Qingsheng YuDepartment of General Surgery, The First Affiliated Hospital of Anhui University of Chinese Medicine Hefei 230031, Anhui, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver fibrosis is the natural stress response of the liver to injury and a critical intermediate stage in the progression of most liver diseases. Here, we first demonstrated

Indexed as

AMPKhepatocellular carcinomaHippoliver fibrosisMetabolic stress

Identifiers

PMID41113966
PMCPMC12531283

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.