ArticleAmerican journal of cancer research2025
Ketamine versus sevoflurane for pediatric intracranial tumor surgery: impact on perioperative stability and postoperative recovery.
Article in American journal of cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
This study compared the clinical efficacy of ketamine and sevoflurane in anesthetic management for pediatric intracranial tumor surgery, focusing on perioperative hemodynamics, inflammatory and stress responses, endotoxin (ET), nitric oxide (NO), oxidative stress, and postoperative recovery. A retrospective analysis was conducted on 229 pediatric patients who underwent intracranial tumor resection between June 2022 and August 2024, of whom 122 received ketamine anesthesia and 107 received sevoflurane. Propensity score matching was applied, yielding 62 patients in each group with balanced baseline characteristics. Perioperative indicators, including mean arterial pressure (MAP), heart rate (HR), C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), epinephrine, cortisol, ET, NO, superoxide dismutase (SOD), and malondialdehyde (MAD), were assessed at five timepoints (T
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