ArticleJournal of biomedical optics2025
Noninvasive quantitative assessment of oral submucosal fibrosis
Article in Journal of biomedical optics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- An organoid-guided roadmap for precision delivery of epigallocatechin gallate in oral submucous fibrosis.Frontiers in bioengineering and biotechnology · 2026Review
- Editorial: Advances in Optical Elastography.Journal of biomedical optics · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Significance: Optical coherence elastography (OCE) is a noninvasive imaging technique with high sensitivity and resolution that can be used for mucocutaneous imaging. Oral submucous fibrosis (OSF) is a chronic disease that has a tendency to become cancerous. Nevertheless, there are a few noninvasive methods for early detection of OSF. Aim: A piezoelectric transducer-based (PZT) OCE technique was devised to noninvasively assess the structural and mechanical properties of mucosa in healthy and fibrotic oral diseases. Approach: We first validated the accuracy and reliability of the OCE system for tissue elasticity detection by means of a heterogeneous agar model. The structural and biomechanical characteristics of the regional tissues were then evaluated by examining the oral mucosa of both healthy and fibrotic SD rats. Results: Normal and fibrotic tissue stiffness differed significantly ( Conclusions: OCE can differentiate between normal and fibrotic tissue based on elasticity and optical properties. Healthy buccal tissues were softer than diseased tissues.
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Registered trials
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