Evidence map›Paper›PMID 41113902›Full record

ReviewRadiology advances2025

Early detection of pancreatic cancer on computed tomography: advancements with deep learning.

Felipe Lopez-Ramirez, Emir A Syailendra, Florent Tixier, Satomi Kawamoto, Elliot K Fishman, Linda C Chu

Abstract readReview
In one paragraph

Review in Radiology advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Felipe Lopez-RamirezThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States.ORCID https://orcid.org/0000-0002-1560-9172
Emir A SyailendraThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States.ORCID https://orcid.org/0000-0001-8608-533X
Florent TixierThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States.ORCID https://orcid.org/0000-0002-9668-6574
Satomi KawamotoThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States.ORCID https://orcid.org/0000-0002-3577-1388
Elliot K FishmanThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States.ORCID https://orcid.org/0000-0002-2567-1658
Linda C ChuThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States.ORCID https://orcid.org/0000-0001-9729-2756

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advancements in artificial intelligence (AI) are transforming medical imaging diagnostics, offering new possibilities for automated pancreatic tumor detection in computed tomography scans. Pancreatic ductal adenocarcinoma continues to be one of the most lethal malignancies, with early detection being critical for improving survival rates. Deep learning models can learn hierarchical feature representations directly from imaging data, enhancing tumor detection accuracy. However, variations in model performance, impaired generalizability, and limited interpretability remain critical barriers to clinical adoption. This article provides a comprehensive overview of deep learning-based pancreatic tumor detection, discussing fundamental concepts, recent advancements, and challenges for clinical adoption. Implementation of deep learning tumor detection models into imaging workflows holds promise for improving early detection rates of pancreatic tumors. Addressing issues of standardization, external validation, and model transparency will be essential to enable the integration of AI into pancreatic cancer screening and diagnostics, ultimately improving early detection and patient outcomes.

Indexed as

artificial intelligencecomputed tomographydeep learningearly detectionpancreatic cancer

Identifiers

PMID41113902
PMCPMC12534903

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.