Evidence map›Paper›PMID 41113883›Full record

ArticleCureus2025

Fixed Dystonia of a Limb: Amputation Could Be a Favourable Outcome.

Rajdeepsinh H Rana, Shivani Virpura, Yogendrasinh Jagatsinh

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rajdeepsinh H RanaGeneral Internal Medicine, Cumberland Infirmary, Carlisle, GBR.
Shivani VirpuraObstetrics and Gynaecology, Cumberland Infirmary, Carlisle, GBR.
Yogendrasinh JagatsinhStroke and Rehabilitation Medicine, Cumberland Infirmary, Carlisle, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fixed dystonia of limb is a rare and complex disorder characterized by abnormal, fixed posturing of a limb, often accompanied by chronic pain. Its etiology remains controversial, with debates surrounding psychogenic versus organic origins. We present the case of a 22-year-old female with a longstanding history of left foot deformity and progressively worsening neuropathic pain, which persisted despite multiple pharmacological treatments, physiotherapy, and psychological interventions. The patient developed severe psychological distress, including suicidal ideation and a self-amputation attempt. After thorough multidisciplinary evaluation, an above-knee amputation was performed. Postoperatively, she experienced complete resolution of preoperative pain, minimal phantom pain managed conservatively, and regained full independence with a prosthesis. Her functional capacity and mental health improved significantly. This case highlights the extreme challenges of managing fixed dystonia and suggests that amputation, although controversial, may be beneficial in highly selected patients with intractable symptoms and significant psychosocial impact.

Indexed as

amputationfdl: fixed dystonia of limbhigh arched foot deformitymicroprocessor-controlled prosthetic kneephantom limb pain

Identifiers

PMID41113883
PMCPMC12527777

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.