ArticleCureus2025
Fixed Dystonia of a Limb: Amputation Could Be a Favourable Outcome.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fixed dystonia of limb is a rare and complex disorder characterized by abnormal, fixed posturing of a limb, often accompanied by chronic pain. Its etiology remains controversial, with debates surrounding psychogenic versus organic origins. We present the case of a 22-year-old female with a longstanding history of left foot deformity and progressively worsening neuropathic pain, which persisted despite multiple pharmacological treatments, physiotherapy, and psychological interventions. The patient developed severe psychological distress, including suicidal ideation and a self-amputation attempt. After thorough multidisciplinary evaluation, an above-knee amputation was performed. Postoperatively, she experienced complete resolution of preoperative pain, minimal phantom pain managed conservatively, and regained full independence with a prosthesis. Her functional capacity and mental health improved significantly. This case highlights the extreme challenges of managing fixed dystonia and suggests that amputation, although controversial, may be beneficial in highly selected patients with intractable symptoms and significant psychosocial impact.
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