ArticleFrontiers in endocrinology2025
Exploring the link between visceral fat and cardiovascular disease in type 2 diabetes: evidence from ct measurements.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- The Relationship Between Visceral Fat Obesity and the Atherogenic Combined Index in Patients with Type 2 Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- The nonlinear association between Body Roundness Index and left ventricular diastolic dysfunction in type 2 diabetes.Frontiers in endocrinology · 2026Article
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Authors and funding
7 authors.
Funding
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Abstract
Background: Visceral fat is a well-established risk factor for cardiovascular disease (CVD) in patients with type 2 diabetes (T2DM). While visceral fat is recognized as a risk factor for CVD in T2DM patients, precise quantification of this relationship using direct CT measurements requires further validation in large populations. This study seeks to examine the cross-sectional association between VFA, as measured by CT, and prevalent CVD in T2DM patients, with the aim of informing risk management strategies in this group. Methods: This cross-sectional study analyzed data from 3,173 T2DM patients who underwent health screenings at Xinxiang First Affiliated Hospital between January 2020 and January 2025. CVD was defined as self-reported physician-diagnosed coronary artery disease, angina pectoris, stroke, congestive heart failure, or myocardial infarction, with verification through follow-up interviews when needed. CVD served as the dependent variable, while VFA, measured by CT, was the independent variable. VFA was categorized into quartiles. The association between VFA and CVD was assessed using univariate and multivariate analyses, smooth curve fitting with generalized additive models, and subgroup analyses. Results: The prevalence of CVD increased progressively across VFA quartiles in T2DM patients. After adjusting for confounders, VFA remained independently associated with prevalent CVD (OR = 1.43, 95% CI: 1.12 - 1.65, Conclusion: VFA is independently associated with prevalent CVD in T2DM patients. Future research should focus on the link between abdominal fat accumulation and CVD in this population.
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