Evidence map›Paper›PMID 41113636›Full record

ArticleFrontiers in microbiology2025

Hammerhead ribozymes directed against mRNA of an essential gene inhibit

Joanna Miszkiewicz-Golec, Ksenia Maximowa, Maciej Łukaszewicz, Dariusz Bartosik, Edward Darżynkiewicz, Joanna Trylska

Abstract read
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In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joanna Miszkiewicz-GolecCentre of New Technologies, University of Warsaw, Warsaw, Poland.
Ksenia MaximowaCentre of New Technologies, University of Warsaw, Warsaw, Poland.
Maciej ŁukaszewiczDivision of Biophysics, Faculty of Physics, Institute of Experimental Physics, University of Warsaw, Warsaw, Poland.
Dariusz BartosikDepartment of Bacterial Genetics, Faculty of Biology, Institute of Microbiology, University of Warsaw, Warsaw, Poland.
Edward DarżynkiewiczCentre of New Technologies, University of Warsaw, Warsaw, Poland.
Joanna TrylskaCentre of New Technologies, University of Warsaw, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aiming to find novel ways to inhibit bacterial growth, we tested hammerhead ribozymes targeting the mRNA

Indexed as

acyl carrier proteinbacterial mRNA targetingcatalytic RNAEscherichia colihammerhead ribozymeRNA-based antimicrobialstranslation inhibition

Identifiers

PMID41113636
PMCPMC12531169

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.