SynthesisFrontiers in pediatrics2025
The predictive value of newborn and infant lung ultrasound score for mechanical ventilation needs: a systematic review and meta-analysis.
Synthesis in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Dynamic bedside lung ultrasound in the diagnosis and management of neonatal lung abscess: a case report.Frontiers in pediatrics · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To investigate the predictive value of neonatal and infant lung ultrasound scores for the need for mechanical ventilation through meta-analysis. Methods: Literature up to October 1, 2024, on neonatal and infant lung ultrasound scores and mechanical ventilation was searched in PubMed, Web of Science, Embase, and The Cochrane Library databases. The diagnostic accuracy of the included studies was evaluated using the Quality Assessment tool for Diagnostic Accuracy Studies. Revman5.4 and StataSE-64 software were employed to calculate the pooled sensitivity, specificity and AUC value of neonatal and infant lung ultrasound scores for predicting the need of mechanical ventilation. Results: The meta-analysis comprised 9 studies (7 prospective studies and 2 retrospective), including a total of 1,746 patients. The LUS score predicted the need for mechanical ventilation. Overall sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio were 74% (95% CI: 66%-81%), 81% (95% CI: 71%-87%), 3.8 (2.4-6.1), 0.32 (0.23-0.46) and 12 (5-6), respectively. The forest plots indicated significant heterogeneity for sensitivity ( Conclusion: Meta-analysis of multivariate categorical variables indicated that the higher the LUS scores, the greater the risk of mechanical ventilation. The combined results of meta-analysis of diagnostic data suggest that LUS score has high accuracy in predicting the need for mechanical ventilation. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/, PROSPERO CRD420251029542.
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