Evidence map›Paper›PMID 41113551›Full record

ArticleEFSA journal. European Food Safety Authority2025

Safety and efficacy of a feed additive consisting of chromium chelate of dl-methionine (Availa® Cr) for all finfish (Zinpro Animal Nutrition Europe, Inc.).

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba and 13 more

Abstract read
In one paragraph

Article in EFSA journal. European Food Safety Authority, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
Roberto Edoardo Villa
Giovanna Azimonti
Eleftherios Bonos
Henrik Christensen
Mojca Durjava
Birgit Dusemund
Ronette Gehring
Boet Glandorf
Maryline Kouba
Marta López-Alonso
Francesca Marcon
Carlo Nebbia
Alena Pechová
Miguel Prieto-Maradona
Ilen Röhe
Katerina Theodoridou
Vasileios Bampidis
Montserrat Anguita
Matteo L Innocenti
Jordi Ortuño
Marianna Kujawa
Joana P Firmino

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a feed additive consisting of chromium chelate of dl-methionine (Availa® Cr) for all finfish. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the additive is safe for salmonids at the maximum proposed use level of 600 mg additive/kg complete feed (corresponding to 0.6 mg Cr/kg complete feed). The FEEDAP Panel was not in the position to conclude on the safety of the use of Availa® Cr in feed for other finfish. The use of the additive in finfish feed at the maximum proposed use level was considered safe for the consumer and for the environment. Regarding user safety, the FEEDAP Panel concluded that the additive is not an eye nor skin irritant, but due to the presence of nickel, the additive is considered a skin and respiratory sensitiser. Inhalation and dermal exposure are considered a risk. The FEEDAP Panel concluded that the additive has the potential to be efficacious in salmonids at 0.2 mg Cr/kg complete feed, and in other finfish at 0.5 mg Cr/kg complete feed.

Indexed as

chromiumdl‐methionineefficacyfinfishsafetysalmonidszootechnical additives

Identifiers

PMID41113551
PMCPMC12528990

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.