Evidence map›Paper›PMID 41113438›Full record

ArticleFrontiers in neuroscience2025

Human

G Schlosser, M Murgaš, G M Godbersen, S Reichel, L Silberbauer, L Nics, D Winkler, T Stimpfl, M Hacker, S Kasper and 3 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02582398 (Influence of Light Exposure on Cerebral Monoamine Oxidase A in Seasonal Affective Disorder and Healthy Controls Measured by PET), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02582398 nacompletednot on this map

Influence of Light Exposure on Cerebral Monoamine Oxidase A in Seasonal Affective Disorder and Healthy Controls Measured by PET

TypeinterventionalSponsorMedical University of ViennaRan2013 to 2017Enrolled99ConditionsSeasonal Affective DisorderArmsLight Therapy, Placebo Light
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

G SchlosserDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
M MurgašDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
G M GodbersenDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
S ReichelDepartment of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
L SilberbauerDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
L NicsDepartment of Biomedical Imaging und Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.
D WinklerDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
T StimpflDepartment of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
M HackerDepartment of Biomedical Imaging und Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.
S KasperDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
D RujescuDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
R LanzenbergerDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
M SpiesDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ketamine is a rapid-acting antidepressant approved in the indication of treatment-resistant depression. As its clinical use expands, identifying underlying molecular mechanisms is essential. The serotonin transporter (SERT) is well known as a primary mechanism of several classes of monoaminergic antidepressants. Binding of ketamine to SERT has been observed Clinical trial registration: http://clinicaltrials.gov, identifier, NCT02582398. EUDAMED number, CIV-AT-13-01-009583.

Indexed as

in vivoketamineneuroimagingpositron emission tomography (PET)serotonin transporter (SERT)

Identifiers

PMID41113438
PMCPMC12528170

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.