ReviewFrontiers in neuroscience2025
Chronotype, cognitive outcomes, and neural dynamics: recent evidence and potential mechanisms with implications for perioperative period.
Review in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The implications of circadian rhythms for anaesthesia.BJA education · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Circadian rhythm plays a fundamental role in regulating biological functions, including sleep-wake preferences, body temperature, hormone secretion, food intake, cognitive function and physical performance. The sleep chronotype, as part of the circadian rhythm, usually refers to an individual's subjective preference for their own sleep-wake cycle. Because of the differences in brain microstructure and resting-state connections between different sleep chronotype, it may lead to differences in individual cognitive function. Concurrently, the pathophysiological mechanisms underlying the association between perioperative circadian misalignment and postoperative cognitive dysfunction (POCD), as well as targeted therapeutic strategies, have garnered increasing attention in recent research. Chronotype exerts regulatory effects on cognitive function via circadian rhythm modulation, neuroinflammatory cascades, and metabolic homeostasis. Perioperative alterations in sleep architecture-including diminished slow-wave sleep (SWS) and circadian desynchronization-may potentiate cognitive deficits and exacerbating neuroinflammation-mediated neuronal apoptosis. This review mainly focuses on the relationship between sleep chronotype and cognitive function as well as perioperative sleep chronotype changes, providing the latest evidence of relevant studies of domestic and foreign. In addition, different sleep patterns and postoperative cognitive dysfunction are prospected, which provides a new direction for exploring the different mechanisms of postoperative cognitive dysfunction in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.