ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2025
[Expression Levels and Clinical Significance of Serum IL-4, IL-5, IL-6, IL-13 and IL-17 in Children With
Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To analyze the expression levels and the clinical significance of serum interleukin (IL)-4, IL-5, IL-6, IL-13 and IL-17 in children with mycoplasma pneumoniae (MP) infection accompanied by airway hyperresponsiveness (AHR). Methods: A total of 120 children diagnosed with MP infection pneumonia and admitted to Nantong First People's Hospital between June 2022 and April 2024 were enrolled in the study group. According to whether their MP infection pneumonia was accompanied by AHR, the participants were divided into an AHR group ( Results: Significant differences were observed among the AHR, non-AHR, and control groups in white blood cell (WBC) count, neutrophil percentage, eosinophil (EOS) count, platelet (PLT) count, C-reactive protein (CRP), FeNO, VPTEF/VE, TPTEF/TE, TI/TE, forced vital capacity (FVC), and forced expiratory volume in one second (FEV₁) (all Conclusion: The levels of serum IL-4, IL-5, IL-6, IL-13, and IL-17 in children with MP infection pneumonia and AHR are abnormally elevated. These cytokines may serve as valuable biomarkers for assessing the risk of AHR in children with MP infection pneumonia.
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