Trial reportSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2025
[Application of Remimazolam in Pediatric Adenoidectomy and Tonsillectomy Anesthesia and Its Effect on Emergence Agitation].
Trial report in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To evaluate the application of different anesthetic drugs-remimazolam (RM) and propofol (PPF)-in anesthesia for pediatric adenoidectomy and tonsillectomy and its effect on emergence agitation. Methods: A total of 120 children undergoing elective adenoidectomy and tonsillectomy under general anesthesia in Xinhua Hospital, Huainan Xinhua Medical Group between December 2022 and August 2024 were enrolled. With a random number table, they were assigned to a PPF group receiving PPF and remifentanil and a RM group receiving RM and remifentanil, with 60 cases in each group. The primary and secondary outcome indicators of the two groups were compared. The primary outcome indicator was the incidence of emergence agitation. Secondary outcome indicators included anesthesia-related parameters, changes in mean arterial pressure (MAP) and heart rate (HR) at different time points during surgery, changes in pediatric anesthesia emergence delirium (PAED) scores at different time points after recovery, changes in Ramsay sedation scores and Face, Legs, Activity, Cry, Consolability (FLACC) pain scores at 2, 4, 12, and 24 hours after surgery, incidence of negative postoperative behavioral changes (NPOBCs) at 7 and 14 days, and adverse events during anesthesia. Results: The incidence rate of emergence agitation was lower in the RM group than that of the PPF group (5.00% vs. 18.33%, Conclusion: RM improves the anesthesia effect and recovery quality of children undergoing adenoidectomy and tonsillectomy, relieves the severity of emergence agitation, reduces the incidence of agitation, and demonstrates good safety.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.