Evidence map›Paper›PMID 41113322›Full record

ArticleOpen forum infectious diseases2025

Comparison of Spectrum Coverage Score-based Antimicrobial Consumption in Acute Care Hospitals Over Eight Years: A Multicentric Study.

Hitoshi Honda, Shutaro Murakami, Takuhiro Kosugi, Akihito Ito, Tetsuma Hata, Yasuhiro Sasaki, Yoshito Hamamoto, Tomoharu Wakugawa, Morihiko Shiroma, Katsunori Nakamura and 2 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hitoshi HondaDepartment of Infectious Diseases, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.ORCID https://orcid.org/0000-0002-4870-0730
Shutaro MurakamiDepartment of Pharmacy, Tokyo Metropolitan Tama Medical Center, Fuchu, Tokyo, Japan.ORCID https://orcid.org/0000-0003-0261-3874
Takuhiro KosugiDepartment of Pharmacy, Yuuai Medical Center, Tomigusuku, Okinawa, Japan.
Akihito ItoDepartment of Pharmacy, Northern Okinawa Medical Center, Nago, Okinawa, Japan.
Tetsuma HataDepartment of Pharmacy, Tokyo Metropolitan Bokutoh Hospital, Sumida, Tokyo, Japan.
Yasuhiro SasakiDepartment of Pharmacy, Tokyo Metropolitan Tama-Nambu Chiiki Hospital, Tama, Tokyo, Japan.ORCID https://orcid.org/0009-0006-6189-3342
Yoshito HamamotoDepartment of Pharmacy, Urasoe General Hospital, Urasoe, Okinawa, Japan.
Tomoharu WakugawaDepartment of Pharmacy, Okinawa Kyodo Hospital, Naha, Okinawa, Japan.
Morihiko ShiromaDepartment of Pharmacy, Nakagami Hospital, Okinawa, Okinawa, Japan.
Katsunori NakamuraDepartment of Pharmacy, University of the Ryukyus Hospital, Ginowan, Okinawa, Japan.ORCID https://orcid.org/0000-0003-0754-410X
Hideo ShiohiraLaboratory of Clinical Pharmacy, Showa Pharmaceutical University, Machida, Tokyo, Japan.
Yasuharu TokudaMuribushi Project for Teaching Hospitals, Urasoe, Okinawa, Japan.ORCID https://orcid.org/0000-0002-9325-7934

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Progress in antimicrobial stewardship programs has introduced new means of assessing antimicrobial use. Days of antibiotic spectrum coverage (DASC) incorporate spectrum data into traditional metrics, such as days of therapy (DOT). This study evaluated DASC across 12 hospitals to assess antimicrobial consumption and the streamlining process. Methods: Data on antimicrobial consumption were collected from 12 hospitals in three regions from April 2016 to March 2024. Trends in streamlining (DASC/DOT) were assessed using linear regression. Spearman's rank-order correlation was used to test for any correlation between DASC/DOT and DOT per 1000 patient-days (PD). Hospital features, including intensive care unit (ICU) capacity and transplant services, were also assessed. Results: In total, data from 96 months revealed median DOT 303.4, DASC 2107.0, and DASC/DOT 7.2. No significant correlation was found between DASC/DOT and DOT per 1000 PD (rho: 0.11; Conclusions: DASC/DOT is a valuable tool for evaluating antimicrobial use and streamlining. Regional and institutional comparisons can help identify facilities requiring more effort to promote antimicrobial stewardship.

Indexed as

antimicrobial stewardshipantimicrobial streamliningdays of antimicrobial spectrum coverage

Identifiers

PMID41113322
PMCPMC12530326

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.