Evidence map›Paper›PMID 41113308›Full record

ArticleClinical case reports2025

When Laughter Knocks You Out: A Case of Laughing-Induced Syncope and a Review of the Literature.

Stephanie Abutu, Mohammad El-Din, Prashanth Raju, Ibrahim Antoun

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stephanie AbutuDepartment of Cardiology Kettering General Hospital Kettering UK.
Mohammad El-DinDepartment of Cardiology Kettering General Hospital Kettering UK.
Prashanth RajuDepartment of Cardiology Kettering General Hospital Kettering UK.
Ibrahim AntounDepartment of Cardiology Kettering General Hospital Kettering UK.ORCID https://orcid.org/0000-0002-4374-7476

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significant implications, particularly in high-risk settings such as driving. This case highlights the diagnostic challenges in identifying this condition, which necessitate a comprehensive evaluation to rule out structural or electrical cardiac abnormalities and confirm the diagnosis through careful monitoring. The proposed pathophysiology involves exaggerated vagal responses or inappropriate sympathetic withdrawal, although the exact mechanisms remain unclear. Management hinges on a tailored, trigger-focused approach, emphasizing patient education and behavioral modifications to prevent a recurrence. Increased awareness of laughter-induced syncope is vital for timely diagnosis, effective management, and the prevention of serious adverse outcomes.

Indexed as

laughing syncopeloss of consiousnessreflex syncopesituational syncope

Identifiers

PMID41113308
PMCPMC12528538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.