Evidence map›Paper›PMID 41113304›Full record

ArticleClinical case reports2025

The Role of Mechanical Economy and Efficiency as Key Drivers of Cardiac Rehabilitation Exercise Performance Improvement in a Patient With Heart Failure and an Implanted CRT-D: A Case Report and Literature Review.

Javier Loureiro Diaz, Praveen Jayaprabha Surendran, Prasobh Jacob, Salma Chbib, Amine Ghram, Liam David Foster, Omar Ibrahim

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Javier Loureiro DiazPerformance and Health Group, Department of Physical Education and Sport, Faculty of Sports Sciences and Physical Education Universidade da Coruña Oleiros Spain.ORCID https://orcid.org/0000-0003-1727-9135
Praveen Jayaprabha SurendranCardiac Rehabilitation Department Heart Hospital. Hamad Medical Corporation Doha Qatar.ORCID https://orcid.org/0000-0002-7417-3559
Prasobh JacobCardiac Rehabilitation Department Heart Hospital. Hamad Medical Corporation Doha Qatar.ORCID https://orcid.org/0000-0003-1153-6305
Salma ChbibPharmacy Department Heart Hospital. Hamad Medical Corporation Doha Qatar.ORCID https://orcid.org/0009-0003-6251-8841
Amine GhramCardiac Rehabilitation Department Heart Hospital. Hamad Medical Corporation Doha Qatar.ORCID https://orcid.org/0000-0002-2851-0753
Liam David FosterRehabilitation Department The View Hospital Doha Qatar.ORCID https://orcid.org/0009-0004-8968-3967
Omar IbrahimCardiac Rehabilitation Department Heart Hospital. Hamad Medical Corporation Doha Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure with reduced ejection fraction leads to exercise intolerance due to central and peripheral dysfunction. Improvements in exercise performance are not fully captured by traditional measures like peak oxygen consumption alone. A 57-year-old male with a complex cardiac medical history of hypertrophic cardiomyopathy with left ventricle non-compaction, Wolff-Parkinson-White syndrome, transient ischemic stroke, and heart failure with reduced ejection fraction with an implanted cardiac resynchronization therapy defibrillator underwent cardiac rehabilitation. Cardiopulmonary exercise testing revealed a non-proportional improvement in peak oxygen consumption (0.3 METs, 9%) versus peak workload (48 W, 61%). Gross mechanical economy and efficiency improved at all physiological thresholds: at ventilatory threshold by 11%, at respiratory compensation point by 60% and 41%, and at peak oxygen consumption by 47% and 33%, respectively. Mechanical economy and mechanical efficiency should be measured and reported for assessing rehabilitation outcomes in heart failure with reduced ejection fraction.

Indexed as

cardiac rehabilitationcardiac resynchronization therapy devicecardiopulmonary exercise testingcardiovascular diseasesexercise capacityheart failuremechanical economymechanical efficiency

Identifiers

PMID41113304
PMCPMC12531118

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.