Evidence map›Paper›PMID 41113234›Full record

ArticleJournal of surgical case reports2025

Atypical diabetic foot ulcer turning into squamous cell carcinoma.

Magdi S Alzir, Hani Mohammed Badahdah, Abdulelah K Alqawlaq

Abstract readCase Reports
In one paragraph

Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Magdi S AlzirOrthopedics and Spine Surgery, International Medical Center, Hail Street, Al-Ruwais, 2172, Jeddah 21451, Saudi Arabia.
Hani Mohammed BadahdahPodiatric Foot & Ankle Surgery, International Medical Center, Hail Street, Al-Ruwais, 2172, Jeddah 21451, Saudi Arabia.
Abdulelah K AlqawlaqCollege of Medicine and Surgery, Batterjee Medical College, Prince Abdullah Al‑Faisal Street, North Obhur, 6231, Jeddah 21442, Saudi Arabia.ORCID https://orcid.org/0009-0006-7844-8288

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous squamous cell carcinoma (cSCC) may rarely arise in chronic diabetic foot ulcers, particularly at unusual sites. We report an 86-year-old man with a chronic retrocalcaneal ulcer refractory to standard care. Vascular imaging showed peripheral arterial disease, and biopsy confirmed well-differentiated cSCC (AJCC 8th edition: pT2Nx), measuring 2.1 × 1.5 cm with 8 mm invasion depth. Staging positron emission tomography/computed tomography and magnetic resonance imaging showed no evidence of metastasis. The patient underwent vascular optimization, wide local excision with clear margins, and local advancement flap coverage. At 4 months, there was no recurrence or metastasis, and wound healing was durable. To the best of our knowledge, this is the first reported case in Saudi Arabia of cSCC developing from a diabetic foot ulcer in the retrocalcaneal region. This case underlines the importance of early biopsy and multidisciplinary evaluation in atypical, non-healing ulcers to avoid delayed diagnosis and ensure optimal patient outcomes.

Indexed as

cutaneous squamous cell carcinomadiabetic foot ulcerMarjolin’s ulcermultidisciplinary managementretrocalcaneal region

Identifiers

PMID41113234
PMCPMC12527822

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.