ArticleDEN open2026
Geriatric 8 Score Predicts Functional Decline After Endoscopic Resection for Upper Gastrointestinal Neoplasms in Older Adults: A Prospective Cohort Study.
Article in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Indications and Curability Criteria for Endoscopic Resection of Early Gastric Cancer in Elderly Patients: Current Standards and Future Perspectives.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Review
- Article
- A study on risk prediction of decline in self-care ability one month after discharge in postoperative colorectal cancer patients based on routine clinical indicators.Frontiers in surgery · 2026Article
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Endoscopic resection (ER) is used in older patients to treat upper gastrointestinal (UGI) neoplasms due to minimal invasiveness and excellent short-term therapeutic outcomes. However, its impact on functional outcomes remains unclear. This study aimed to identify functional-decline predictors post-ER in older patients. Methods: This prospective, single-center cohort study included patients aged ≥75 years undergoing ER for UGI neoplasms between April 2017 and December 2021. Cognitive and physical functions were assessed using the Mini-Mental State Examination (MMSE) and Instrumental Activities of Daily Living (IADL) scales, before and 6-9 months post-ER. Functional decline was defined as a decrease of ≥3 points in MMSE or ≥1 point in IADL. Scores of geriatric assessment tools, including the Geriatric 8 (G8), Vulnerable Elders Survey-13 (VES-13), Flemish Triage Risk Screening Tool, and Mini-Cognitive Assessment Instrument (Mini-Cog), were evaluated as potential functional-decline predictors. Results: Of 202 patients, 37 (18.3%) experienced functional decline post-ER. In multivariate analysis, poor G8 scores (≤14) were independent risk factors for functional decline (odds ratio: 2.64, 95% confidence interval: 1.02-6.84, Conclusions: Preoperative G8 scores may serve as functional-decline predictors in older patients undergoing ER for UGI neoplasms. A preoperative G8 assessment could facilitate risk-based treatment decisions from the perspective of functional outcomes in this vulnerable population.
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