Evidence map›Paper›PMID 41113135›Full record

ArticleFrontiers in surgery2025

Impact of preoperative bowel preparation methods on anastomotic leakage and intestinal motility recovery in laparoscope-assisted heart-shaped anastomosis.

Pei Zhang, Decheng Wei, Jian Bian, Shijin Qi

Abstract read
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Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Pei ZhangDepartment of General Surgery, Anhui Provincial Children's Hospital, Hefei, Anhui, China.
Decheng WeiDepartment of General Surgery, Anhui Provincial Children's Hospital, Hefei, Anhui, China.
Jian BianDepartment of General Surgery, Anhui Provincial Children's Hospital, Hefei, Anhui, China.
Shijin QiDepartment of General Surgery, Anhui Provincial Children's Hospital, Hefei, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hirschsprung's disease (HSCR) is a congenital bowel-obstructive disorder caused by the absence of enteric ganglion cells. While laparoscope-assisted heart-shaped anastomosis (LHSA) shows promise in surgical management, risks like anastomotic leakage persist. Preoperative bowel preparation is key in optimizing surgery outcomes. This study evaluates the efficacy of mechanical bowel preparation (MBP) vs. MBP combined with oral antibiotics (OA) in reducing postoperative complications and improving recovery. Methods: This retrospective cohort study involved 215 HSCR patients who underwent LHSA between June 2010 and June 2023. Patients were divided into two groups: MBP + OA and MBP alone. Outcomes measured included anastomotic leakage, surgical site infections (SSIs), postoperative intestinal motility, inflammatory markers, postoperative recovery markers, and quality of life assessments. Results: The OA + MBP group demonstrated a significant reduction in SSIs (2.65% vs. 9.80%, Conclusion: The addition of oral antibiotics to mechanical bowel preparation significantly decreases the risk of SSIs, enhances recovery, and improves both inflammatory profiles and bowel function in LHSA.

Indexed as

Hirschsprung's diseaselaparoscope-assisted heart-shaped anastomosismechanical bowel preparationoral antibioticspostoperative recoverysurgical site infection

Identifiers

PMID41113135
PMCPMC12531185

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.