ReviewFrontiers in surgery2025
Multidisciplinary protocols are an important part of enhanced recovery after major lower extremity amputation.
Review in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Effective Interventions in Restoring Mobility and Relieving Pain After Lower Limb Amputation.Journal of orthopaedics and sports medicine · 2026Article
- Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Major lower extremity amputation (MLEA) remains a high-risk procedure with significant implications for patient morbidity, mortality, and long-term functional independence. Optimizing outcomes for this vulnerable population requires a comprehensive, multidisciplinary approach guided by evidence-based perioperative care pathways. Enhanced Recovery After Surgery (ERAS) protocols offer a structured framework to improve recovery trajectories by standardizing key elements of care. This review examines the application of ERAS principles to the MLEA population, synthesizing current literature on preoperative assessment and patient selection, multimodal analgesia, early mobilization strategies, and coordinated post-discharge planning. By integrating findings from consensus statements and pilot studies, we demonstrate how tailored ERAS-based multidisciplinary protocols can reduce complications, enhance functional recovery, and promote equity in outcomes. The development and implementation of such structured care pathways represent a critical step toward improving the standard of care for patients undergoing major lower extremity amputation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.