ArticleInternational journal of women's health2025
Global, Regional, and National Burdens of Inflammatory Bowel Disease in Women of Reproductive Age (15-49 Years) from 1992 to 2021.
Article in International journal of women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Inflammatory bowel disease (IBD) substantially affects women of reproductive age, yet global trends and burdens within this group remain inadequately explored. This study evaluates the global, regional, and national burdens of IBD among women aged 15-49 from 1992 to 2021, with projections to 2030. Methods: Data were obtained from the Global Burden of Disease (GBD) 2021 study. We analyzed incidence, mortality, and disability-adjusted life years (DALYs) of IBD across age groups. Trends over time were assessed using estimated annual percentage change (EAPC), and socio-demographic index (SDI) levels were applied to examine disparities related to development status. Results: In 2021, the global IBD cases among women aged 15-49 reached 98,974.56, representing a 55.04% increase since 1992. Mortality remained relatively stable, with 2,586.76 deaths in 2021, while DALYs rose by 38.53% to 281,580.36. High SDI regions exhibited higher incidence and DALYs rates but lower mortality rates. Conversely, low and middle SDI regions faced greater challenges, with higher mortality and DALYs rates despite lower incidence rates. By 2030, projections suggest a slight decline in global incidence rates, reducing total cases to approximately 94,773. Mortality rates are anticipated to remain stable, though deaths may slightly increase to 2781. DALYs are projected to rise marginally to 284,508 by 2030. Conclusion: The global burden of IBD among women of reproductive age has markedly increased, displaying considerable regional and socio-demographic variations. Targeted public health strategies are crucial, particularly in regions with lower development levels.
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