Evidence map›Paper›PMID 41113016›Full record

ArticleAmerican journal of translational research2025

Repeated low-intensity red light therapy for childhood myopia: a retrospective cohort study.

Meihua Tan, Binbin Li, Zhe Xu, Donghua Wu, Jinrong Liu, Wei Tang, Fengling Xu

Abstract read
In one paragraph

Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Meihua TanDepartment of Ophthalmology, Ganzhou People's Hospital Ganzhou 341000, Jiangxi, China.
Binbin LiDepartment of Ophthalmology, Ganzhou People's Hospital Ganzhou 341000, Jiangxi, China.
Zhe XuDepartment of Ophthalmology, Ganzhou People's Hospital Ganzhou 341000, Jiangxi, China.
Donghua WuDepartment of Ophthalmology, Ganzhou People's Hospital Ganzhou 341000, Jiangxi, China.
Jinrong LiuDepartment of Ophthalmology, Ganzhou People's Hospital Ganzhou 341000, Jiangxi, China.
Wei TangDepartment of Ophthalmology, Ganzhou People's Hospital Ganzhou 341000, Jiangxi, China.
Fengling XuDepartment of Ophthalmology, Ganzhou People's Hospital Ganzhou 341000, Jiangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the efficacy and safety of repeated low-intensity red light (RLRL) therapy in slowing myopia progression and improving accommodative function in children.

methodsThis retrospective cohort study reviewed electronic medical records of 202 myopic children aged 6-12 years treated at Ganzhou People's Hospital between October 2022 and October 2024. Participants were assigned to an RLRL group (n = 101; 650 nm, 1600 lx, 3 min, twice daily) or a control group (n = 101; single-vision spectacles only). Primary outcomes included axial length and spherical equivalent refraction. Secondary outcomes were uncorrected and best-corrected visual acuity, macular choroidal thickness, accommodative amplitude and facility, intraocular pressure (IOP), and corneal endothelial cell density (ECD).

resultsBaseline demographics and ocular characteristics were comparable between groups (all P > 0.05). Up to 12 months, the RLRL group exhibited significantly less axial elongation and myopic refractive progression (P < 0.05 from 6 months onward), greater improvement in uncorrected visual acuity, thicker macular choroid, and enhanced accommodative function compared to controls (all P < 0.05). No significant between-group differences were observed in IOP or corneal ECD (both P > 0.05).

conclusionRLRL therapy significantly slowed myopia progression and improved visual and accommodative function in children over 12 months, with no major safety concerns. These findings support RLRL as a promising, safe intervention for pediatric myopia control.

Indexed as

axial lengthMyopia controlocular safetypediatric ophthalmologyrefractive errorrepeated low-intensity red-light therapy

Identifiers

PMID41113016
PMCPMC12531544

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.