ArticleClinical parkinsonism & related disorders2025
Nonmotor symptoms in Parkinson's disease patients in South Asia: A systematic review and meta-analysis.
Article in Clinical parkinsonism & related disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Hoehn and Yahr Stage and Non-Motor Symptom Burden in Parkinson's Disease: A Cross-Sectional Study in Peru.Medicina (Kaunas, Lithuania) · 2026Article
- Cerebellar oligodendrocytic α-synuclein pathology and dentate nucleus neuronal hypertrophy in Parkinson's disease.Scientific reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The most common movement disorder and neurodegenerative disorder that progresses over time, Parkinson's disease, has both motor and nonmotor symptoms. Asia is home to half of the world's elderly population, and Parkinson's disease is a common condition in this demographic. Objectives: We aimed to estimate the pooled prevalence of nonmotor symptoms among Parkinson's disease patients in South Asia based on the available literature. Methods: The study protocol was registered on PROSPERO with reference number CRD42024579956. Databases were searched for observational studies from 2000 to 2024 in English that have assessed the prevalence of nonmotor symptoms among Parkinson's disease patients in South Asia via validated tools. High-quality studies were included after quality assessment. A random-effects model was used to calculate the pooled prevalence with a 95 % confidence interval. Results: Among the 50 articles (4931 participants) included in the review, 9 (862 participants) used the Nonmotor Symptoms Questionnaire, 9 (803 participants) used the Nonmotor Symptoms Scale, 2 (171 participants) used both, and the remaining 30 (3095 participants) used other validated tools to assess nonmotor symptoms in South Asian patients with Parkinson's disease. The prevalence of nonmotor symptoms was high, with nocturia being the most prevalent. Psychological symptoms were frequently explained via other tools. Conclusions: Our research is among the few clinical accounts in the literature of the prevalence of nonmotor stmptoms in South Asian Parkinson's disease patients. Although the heterogeneity of the results could not be fully explained, our study could significantly enhance the understanding of symptoms, leading to more tailored therapeutic and diagnostic strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.