Evidence map›Paper›PMID 41112943›Full record

ReviewInternational journal of nanomedicine2025

Liposome-Based Nanoparticle Delivery Systems for Lung Diseases: Opportunities and Challenges.

Xi Zhang, Shiju Tu, Jiahua Tian, Yan Liang, Yiling An, Tianyou Zhang, Hongyun Guan, Bo Xiong, Li Qin, Yunfei Li and 1 more

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xi Zhang *Department of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, Guizhou, People's Republic of China.
Shiju Tu *Department of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, Guizhou, People's Republic of China.
Jiahua Tian *Department of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, Guizhou, People's Republic of China.
Yan LiangDepartment of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, Guizhou, People's Republic of China.
Yiling AnDepartment of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, Guizhou, People's Republic of China.
Tianyou ZhangDepartment of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, Guizhou, People's Republic of China.
Hongyun GuanDepartment of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, Guizhou, People's Republic of China.
Bo XiongDepartment of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, Guizhou, People's Republic of China.
Li QinDepartment of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, Guizhou, People's Republic of China.
Yunfei LiDepartment of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, Guizhou, People's Republic of China.
Ling GongDepartment of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, Guizhou, People's Republic of China.ORCID 0000-0001-5816-3716

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of the lungs as one of the most important organs in the body cannot be overstated. When disease occurs in the lungs, due to the special physiological structure and barriers of the lungs, many drugs is often required to maintain the required blood concentration, which brings unbearable adverse drug reactions to the patients, reduces the tolerance of the patients to the drugs, and affects the effect of disease treatment. As a mature delivery system, liposomes are widely used in major fields, and more importantly, liposome-delivered drugs have been utilized in clinical treatments, effectively reducing the side effects of drugs and achieving excellent efficacy. This review describes in detail the physiological structure and barriers of the lungs and the structure of liposomes; then summarizes the application of liposomes in different lung diseases, as well as its drawbacks and advantages. Finally, we suggest that liposome-delivered nucleic acids are expected to be a new trend and approach for the treatment of lung diseases.

Indexed as

Drug Delivery SystemsLiposomesLung DiseasesNanoparticle Drug Delivery SystemNanoparticlesAnimalsHumansLungNucleic AcidsLiposomesNanoparticle Drug Delivery SystemNucleic Acidsdelivery systemliposomesLung anatomylung disease

Identifiers

PMID41112943
PMCPMC12535190

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.