Evidence map›Paper›PMID 41112852›Full record

ArticleACG case reports journal2025

Neuroendocrine Tumor of the Terminal Ileum Presenting as Refractory Crohn's Disease: A Diagnostic Challenge.

Mohammad Abuassi, Saar Peles, Bellal Alfar, Aiman Obed

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohammad AbuassiDepartment of Internal Medicine, University of Central Florida, Gainesville, FL.ORCID https://orcid.org/0000-0002-9728-6310
Saar PelesUniversity of Central Florida College of Medicine, Orlando, FL.ORCID https://orcid.org/0009-0000-0125-5505
Bellal AlfarDepartment of General Surgery, Jordan Hospital, Ibn Sina University for Medical Sciences, Amman, Jordan.
Aiman ObedDepartment of Hepatobiliary and Transplant Surgery, Jordan Hospital, Ibn Sina University for Medical Sciences, Amman, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroendocrine tumors (NETs) can mimic inflammatory bowel diseases like Crohn's, often delaying diagnosis. We report a case of a 56-year-old woman with abdominal pain, diarrhea, and weight loss initially treated as Crohn's disease. Despite immunomodulatory therapy, symptoms persisted. Imaging revealed ileal strictures and a suspicious mass. Surgical resection was performed, and histopathology confirmed a Grade 1 well-differentiated ileal NET (pT4 pN1) with lymphovascular and perineural invasion. The patient was referred for oncology follow-up. This case highlights the need to consider NETs in patients with gastrointestinal symptoms that mimic Crohn's disease but fail to respond to standard therapies.

Indexed as

Crohn's diseaseGastrointestinal neoplasmsneuroendocrine tumor

Identifiers

PMID41112852
PMCPMC12528589

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.