Evidence map›Paper›PMID 41112804›Full record

ArticleBiomedical optics express2025

Binocular adaptive optics visual simulator with convergence control.

Santiago Sager, Adrián Gambín, Pedro M Prieto, Pablo Artal

Abstract read
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Santiago SagerLaboratorio de Óptica, Centro de Investigación en Óptica y Nanofísica (CiOyN), Universidad de Murcia, Campus de Espinardo (Ed. 34), 30010 Murcia, Spain.ORCID https://orcid.org/0000-0001-5682-8630
Adrián GambínLaboratorio de Óptica, Centro de Investigación en Óptica y Nanofísica (CiOyN), Universidad de Murcia, Campus de Espinardo (Ed. 34), 30010 Murcia, Spain.
Pedro M PrietoLaboratorio de Óptica, Centro de Investigación en Óptica y Nanofísica (CiOyN), Universidad de Murcia, Campus de Espinardo (Ed. 34), 30010 Murcia, Spain.ORCID https://orcid.org/0000-0001-6192-4053
Pablo ArtalLaboratorio de Óptica, Centro de Investigación en Óptica y Nanofísica (CiOyN), Universidad de Murcia, Campus de Espinardo (Ed. 34), 30010 Murcia, Spain.ORCID https://orcid.org/0000-0003-1284-6591

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a new generation of binocular adaptive optics visual simulator (B-AOVS). As in earlier versions, the system optimizes hardware use by managing both eyes with a single intensity spatial light modulator for pupil control and a single phase modulator for aberration manipulation, both of them based on liquid-crystal-on-silicon (LCoS) technology. A single Hartmann-Shack sensor measures refraction and aberrations in both eyes, and a single tunable lens extends the correction and measurement range. Only the stimulus generation module is duplicated, using two HD microdisplays to ensure adequate resolution and field of view. The main improvement in this prototype is the addition of a motorized twin-periscope system that adjusts the vergence angle of the stimuli, enabling more realistic visual testing at multiple distances. Among other applications, this feature paves the way for studies requiring accommodative changes that would be otherwise unfeasible due to the vergence-accommodation conflict. For this particular reason, studies with past generations of B-AOVS were typically carried out in presbyopes or cyclopleged subjects, on the assumption that avoiding the conflict by preventing accommodation would render convergence irrelevant. To specifically test this assumption, our first use of the prototype was to measure defocus curves in one presbyopic and four cyclopleged subjects for varying levels of induced spherical aberration, with and without convergence control. In this non-accommodative situation, convergence showed minimal influence, as defocus curves remained similar, and therefore the validity of previous studies with B-AOVS under fixed convergence conditions remains unchallenged. Beyond this case, the new vergence control system enables accurate 3D stimulus presentation for visual simulation and opens avenues to study the impact of aberrations on the vergence-accommodation conflict.

Identifiers

PMID41112804
PMCPMC12532328

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.