Evidence map›Paper›PMID 41112760›Full record

ArticlePeerJ2025

Prediction of pathological complete response to neoadjuvant chemotherapy for invasive breast cancers based on longitudinal ultrasound and superb microvascular imaging: a single-center retrospective study.

Yanling Zuo, Yongtao Zhan, Jie Zhou, Haoming Xia, Tao Li, Fan Zhou, Chunyue Luo, Huafeng Zeng, Yingjia Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yanling Zuo *Department of Ultrasound, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Yongtao Zhan *Department of Breast Surgery, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, Guangdong, China.
Jie ZhouDepartment of Breast Surgery, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, Guangdong, China.
Haoming XiaDepartment of Breast Surgery, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, Guangdong, China.
Tao LiDepartment of Ultrasound, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, Guangdong, China.
Fan ZhouDepartment of Radiology, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, China.
Chunyue LuoDepartment of Ultrasound, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, Guangdong, China.
Huafeng ZengDepartment of Ultrasound, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, Guangdong, China.
Yingjia LiDepartment of Ultrasound, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To examine whether dynamic alterations in conventional ultrasound (US) and superb microvascular imaging (SMI) can act as predictors of pathological complete response (pCR) following neoadjuvant chemotherapy (NAC) in breast cancer (BC). Methods: This single-center, retrospective study included women with invasive BC who underwent NAC between January 2022 and December 2024. The features of conventional US and SMI characteristics of BC were analyzed before NAC and the change (Δ) after two cycles. Multivariate logistic regression analysis (Forward, Wald, Results: Before NAC, the pCR group exhibited significantly higher negative rates for the estrogen receptor (ER) and progesterone receptor (PR). ( Conclusion: The baseline status of US and SMI, as well as the longitudinal changes, demonstrated good predictive performance for pCR in BC following NAC.

Indexed as

Breast NeoplasmsNeoadjuvant TherapyUltrasonography, MammaryAdultAgedChemotherapy, AdjuvantFemaleHumansMicrovesselsMiddle AgedRetrospective StudiesUltrasonographyBreast cancerNeoadjuvant chemotherapyPathological complete responseSuperb microvascular imagingUltrasound

Identifiers

PMID41112760
PMCPMC12533535

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.