Evidence map›Paper›PMID 41112743›Full record

ArticleFrontiers in nutrition2025

Global burden of four cardiovascular diseases attributable to low fruits and vegetables intake, 1990-2021, with a forecast to 2044.

Xin He, JiaXin Huang, Hua Cao, Zhangbo Cheng

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xin He *Shengli Clinical Medical College, Fujian Medical University, Fuzhou, China.
JiaXin Huang *Shengli Clinical Medical College, Fujian Medical University, Fuzhou, China.
Hua CaoShengli Clinical Medical College, Fujian Medical University, Fuzhou, China.
Zhangbo ChengShengli Clinical Medical College, Fujian Medical University, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiovascular diseases (CVDs) remain the leading global cause of death. The contribution of inadequate fruits and vegetables (F&V) intake to specific CVD subtypes has not been well characterized across places and time. Methods: Using Global Burden of Disease (GBD) 2021 estimates for 204 countries/territories, we have quantified deaths and disability-adjusted life years (DALYs) from ischaemic heart disease (IHD), hypertensive heart disease (HHD), peripheral artery disease (PAD), and aortic aneurysm (AA) attributable to low fruit or low vegetables intake (1990-2021). We have assessed age-standardized mortality and DALY rates (ASMR, ASDR) and temporal trends via estimated annual percentage change (EAPC), examined patterns by age, sex, and Sociodemographic Index (SDI), decomposed changes into demographics versus epidemiologic effects, and generated forecasts to 2044 using Nordpred. Results: In 2021, inadequate F&V intake accounted for a substantial CVD burden worldwide. IHD and HHD dominated deaths and DALYs. Although ASMRs and ASDRs generally declined, absolute deaths rose, driven largely by population aging. AA, PAD, and IHD burdens were higher in men, whereas HHD burden was higher in women. Middle- and low-SDI settings carried greater IHD and HHD burdens, while AA and PAD were more prominent in high-SDI regions. Notably, HHD mortality attributable to low fruits intake increased across all SDI strata. Decomposition analyses indicated aging as the principal driver of rising deaths in high-SDI regions and combined effects of population growth and adverse epidemiologic change in lower-SDI regions. Projections suggested continued increases in deaths with relatively stable ASMRs through 2044. Conclusion: Despite improvements in age-standardized rates, persistent dietary risks and demographic aging sustained a high, uneven burden of diet-related CVDs. Equitable, population-level policies to improve F&V affordability and access-particularly in lower-SDI regions-are essential to curb future cardiovascular mortality.

Indexed as

cardiovascular diseasesdietary risk factorsfruits and vegetables intakeglobal burden of diseasemortality trendsSocio-demographic Index (SDI)

Identifiers

PMID41112743
PMCPMC12527854

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.