Ultraslow versus slow-rate shockwave lithotripsy in the management of renal stone: A randomized controlled trial.

Introduction: This study aimed to evaluate the efficacy of ultraslow shockwave (SW) lithotripsy compared with slow-rate SW lithotripsy (SWL) in the management of renal stones using a common power ramping protocol. Methods: This randomized trial enrolled patients with solitary renal calculus ≤2 cms between December 2021 and February 2024. Ultraslow lithotripsy (40 patients) was applied at a rate of 30 shocks per minute and slowrate lithotripsy (40 patients) was applied at a rate of 60 shocks per minute. Common power ramping protocol was followed for both the groups. Up to a maximum of three sessions were carried out with follow-up at 3 months after the last session. The primary outcome was the stone-free rate. Results: The overall stone-free rate (SFR) was 77.5% in the ultraslow arm and 72.5% in the slow-rate arm ( Conclusions: In the setting of an electromagnetic lithotripter with a common ramping protocol and equal energy SWs, both ultraslow and slowrate SWL achieved a comparable overall stone-free rate with a similar safety profile. Higher number of patients in the ultraslow arm, almost double that of the slow arm, attained stone-free status after the first session itself with significantly fewer shocks.