ArticleJB & JS open access
The Use of Navigation During Total Knee Replacement Improves Precision in Achieving Mechanical Alignment in Obese Patients: A Short-Term Multicenter Randomized Clinical Trial.
Article in JB & JS open access. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Mechanically aligned total knee arthroplasty demonstrates acceptable outcomes in obese patients, with insufficient evidence for alternative alignment strategies: A systematic review.Journal of experimental orthopaedics · 2026Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Obesity (body mass index ≥30 kg/m Methods: A total of 159 obese patients with symptomatic KOA were randomized 1:1 at 2 hospitals to undergo TKA with either NAS or conventional guides. Mechanical axis alignment was assessed 1 year postoperatively using long-standing radiographs. Secondary end points included femoral and tibial component alignment, surgical time, complications, range of motion, Knee Society Score, Western Ontario and McMaster Universities Osteoarthritis Index, visual analog scale, and EuroQol-5D. Results: In total, 154 patients were analyzed. Proper mechanical axis alignment (180° ± 3°) was achieved in 69% of NAS cases vs. 47% in controls (p = 0.006; OR = 2.5; 95% confidence interval: 1.29-4.83). The mean deviation was -1.59° (SD 3.02) in NAS vs. -2.15° (SD 3.56) in controls. Tibial alignment outliers occurred in 16% (12/73) of NAS vs. 32% (23/71) in controls (p = 0.026). Surgical time was longer with NAS (70 min [interquartile range (IQR) 63-76] vs. 59 min [IQR 55-67], p < 0.001). No differences were found in complications or hospital stay. Functional outcomes improved similarly in both groups at 1 year. Conclusion: NAS significantly improves precision in achieving mechanical alignment in obese patients undergoing TKA. Despite similar clinical outcomes, NAS offers superior radiographic accuracy. Longer term studies are needed to assess effects on implant survival and patient-reported outcomes. Level of Evidence: Level I. See Instructions for Authors for a complete description of levels of evidence.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.