A retrospective study on factors associated with COVID-19 vaccine refusal among individuals aged 15 years and above in the general population of Bamenda I sub-division, Cameroon.

Background: By the end of 2020, several vaccines aimed at combating COVID-19 were authorized for widespread immunization. The aim of this study was to assess the factors that were associated with COVID-19 Vaccine refusal in Bamenda I. Method: This was a retrospective study carried out in the subdivision of Bamenda I, from March to June 2024, through interviews and questionnaires in which participants were asked to recall important events during the COVID-19 pandemic. A questionnaire-based survey was conducted to ensure diverse representation in the community study. The questionnaire comprised four sections: socio-demographic characteristics, knowledge about COVID-19 and vaccines, attitudes toward COVID-19, and beliefs about the vaccine. Data were collected during community gatherings, such as focus group discussions and training sessions, and also through Google Forms via the Kobo tool for participants with Android phones. Data were then transferred to SPSS for analysis, using the Pearson chi-square test to examine associations, with Results: Our results show that 42.40% participants had high knowledge about COVID-19, 39.40% had moderate knowledge while 18.20% had low knowledge. Their vaccination status, showed that, just 12.10% were vaccinated, and 87.90% were unvaccinated. Socio-demographic factors like age, gender, and education recorded significant associations with respect to vaccine refusal Conclusion: The study highlights significant knowledge gaps and widespread concerns about vaccine safety among the population in Bamenda I, indicating a need for targeted educational interventions to improve vaccination rates.