ArticleWorld journal of psychiatry2025
Suicide attempt predictors among adolescents exhibiting non-suicidal self-injury: A six-week follow-up open study.
Article in World journal of psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Inflammation and suicide risk in adolescents with self-injury: Expanding the role of mental health nursing.World journal of psychiatry · 2026Article
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9 authors.
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Abstract
backgroundNon-suicidal self-injury (NSSI) in adolescents is a strong predictor of suicide and a significant mental health problem worldwide. Previous studies have identified various risk factors for NSSI. However, studies have not explored the association between inflammatory factors and NSSI in adolescents.
aimTo investigate inflammatory marker changes post-antidepressant treatment and their association with suicide risk in NSSI adolescents.
methodsThe study enrolled 68 adolescents with NSSI behaviors. The participants were divided into high and low suicide risk groups (
resultsThe high suicide risk group exhibited higher levels of interferon (IFN)-α and interleukin (IL)-10 than the low suicide risk group. Scores on the Hamilton Anxiety Rating Scale, Hamilton Depression Rating Scale, and Insomnia Severity Index decreased significantly post-treatment. Tumor necrosis factor-α, IL-10, IL-6, IL-1, and IL-12 levels decreased, whereas IFN-γ, IL-4, and IFN-α levels increased. IL-10 levels were correlated with the severity of suicide risk factors.
conclusionAdolescents with NSSI exhibit distinct inflammatory markers based on suicide risk, which change following treatment. Moreover, IL-10 levels are associated with suicide risk. These biomarkers may help assess suicide risk in clinical settings.
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