Evidence map›Paper›PMID 41112606›Full record

ArticleWorld journal of psychiatry2025

Anxiety and depression in patients with hepatobiliary and pancreatic malignancies: Influence of disease stage and psychosocial factors.

Xiao Yu, Xiao He, Shuai Wang

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Article in World journal of psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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2 citing papers in PubMed.

  1. Article
  2. Patient-controlled subcutaneous analgesia with hydromorphone in cancer pain management.Frontiers in pain research (Lausanne, Switzerland) · 2025
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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Xiao YuDepartment of Hepatobiliary Surgery, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou 434020, Hubei Province, China.
Xiao HeDepartment of Psychiatry, Jingzhou Mental Health Center, Jingzhou 434000, Hubei Province, China.
Shuai WangDepartment of Hepatobiliary Surgery, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou 434020, Hubei Province, China. l10095@yangtzeu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatobiliary and pancreatic malignancies, with their aggressiveness and poor prognosis, often trigger anxiety and depression in patients, but the roles of disease stage and psychosocial factors in this remain unclear.

aimTo explore the clinical characteristics and factors influencing comorbid anxiety and depression in patients with malignant liver, gallbladder, and pancreatic tumors.

methodsThis study enrolled 150 participants, including 48 patients with early stage (IA-IB) hepatobiliary and pancreatic malignancies (Control Group 1), 52 patients with middle-stage (IIA-IIIA) tumors (Observation Group), and 50 healthy individuals undergoing physical examination (Control Group 2). Anxiety and depression detection rates, and scores on the Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), and Life Event Scale were compared across groups. The factors influencing emotion of each patient were collected and analyzed by group.

resultsAnxiety and depression detection rates were significantly higher in the Observation Group (82.69% and 92.31%, respectively;

conclusionPatients with hepatobiliary and pancreatic malignancies are prone to comorbid anxiety and depression, with increasing severity in the later disease stages. Despite the relatively small sample size, our findings suggest the need for psychological assessments and interventions in comprehensive cancer care. Future studies should consider expanding the sample size to enhance generalizability. Strengthening psychosocial support may improve patient outcomes and quality of life.

Indexed as

AnxietyClinical characteristicsComorbidityDepressionHepatobiliary and pancreatic malignanciesPsychological factors

Identifiers

PMID41112606
PMCPMC12531972

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