ArticleJournal of manufacturing science and engineering2025
Data-Driven Optimization of Bioink Formulations for Extrusion-Based Bioprinting: A Predictive Modeling Approach.
Article in Journal of manufacturing science and engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- The Next Phase of 3D Bioprinting: AI-Native Systems-A Narrative Review.Journal of functional biomaterials · 2026Review
- Feasible Regions of Nozzle Temperature, Extrusion Pressure, and Printing Speed in Extrusion-Based Printing Using a Sodium Alginate-Carboxymethylcellulose-Collagen I Bioink.Biomimetics (Basel, Switzerland) · 2026Article
- 3D biofabricated in vitro models as new approach methodologies for animal alternatives.npj biomedical innovations · 2026Review
- Three-Dimensional Printing and Bioprinting Strategies for Cardiovascular Constructs: From Printing Inks to Vascularization.Polymers · 2025Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The field of tissue engineering has significantly advanced with the development of extrusion-based bioprinting. This technique utilizes shear forces to generate filaments for fabricating intricate structures. The printability and structural integrity of bioprinted constructs rely heavily on the rheological properties of bioinks, particularly viscosity, which varies with the shear rate for non-Newtonian materials. Since the shear rate at the nozzle tip fluctuates during extrusion, it is essential to understand how bioink composition influences this behavior. This study investigates the rheological behavior of ALGEC bioinks, a novel formulation composed of ALginate, GElatin, and 2,2,6,6-Tetramethylpiperidine 1-oxyl (TEMPO)-oxidized nanofibrillated cellulose (TO-NFC). The bioinks were prepared with varying concentrations: alginate (0-5.25%), gelatin (0-5.25%), and TO-NFC (0-1.5%), with a maximum total solid content of 8%. Viscosity was conducted over shear rates ranging from 0.1 to 100 s
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.