Evidence map›Paper›PMID 41112524›Full record

ReviewGenes & diseases2026

The roles of cell cycle proteins in regulating the tumor immune microenvironment.

Qingbo Zhu, Xiaoli Wei, Ziting Qu, Lili Lu, Yiyin Zhang, Hua Wang

Abstract readReview
In one paragraph

Review in Genes & diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qingbo ZhuDepartment of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China.
Xiaoli WeiDepartment of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China.
Ziting QuDepartment of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China.
Lili LuDepartment of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China.
Yiyin ZhangDepartment of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China.
Hua WangDepartment of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have shown that in addition to regulating the growth of tumor cells, cell cycle proteins can also regulate immune cells and factors in the tumor immune microenvironment (TIME), thus playing a role in regulating tumor immunity. This review summarizes the relevant mechanisms of cell cycle regulatory proteins in TIME regulation. The development of effective drugs against relevant therapeutic targets may be a hot research topic for the next generation of antitumor immunotherapy.

Indexed as

Cell cycle proteinsMechanismsNegativePositiveTumor immune microenvironment

Identifiers

PMID41112524
PMCPMC12528906

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.