Evidence map›Paper›PMID 41112493›Full record

ArticleJournal of vitreoretinal diseases2025

Efficacy of Intravitreal Pegcetacoplan vs Avacincaptad Pegol in Patients With Geographic Atrophy.

Paul Hahn, David Eichenbaum, Dilsher S Dhoot, Charles C Wykoff, Michael A Klufas, Michele Intorcia, Daniel Jones, Sujata P Sarda, Priyanka Bobbili, Rose Chang and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of vitreoretinal diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Paul HahnNJ Retina, Teaneck, NJ, USA.ORCID https://orcid.org/0000-0002-6574-388X
David EichenbaumRetina Vitreous Associates of Florida, St. Petersburg, FL, USA.ORCID https://orcid.org/0000-0003-0654-0668
Dilsher S DhootCalifornia Retinal Consultants/Retina Consultants of America, Santa Barbara, CA, USA.
Charles C WykoffRetina Consultants of Texas, Retina Consultants of America, Houston, TX, USA.ORCID https://orcid.org/0000-0001-7756-5091
Michael A KlufasMid Atlantic Retina, Wills Eye Hospital, Philadelphia, PA, USA.
Michele IntorciaApellis Pharmaceuticals, Waltham, MA, USA.
Daniel JonesApellis Pharmaceuticals, Waltham, MA, USA.
Sujata P SardaApellis Pharmaceuticals, Waltham, MA, USA.
Priyanka BobbiliAnalysis Group, Inc., Boston, MA, USA.
Rose ChangAnalysis Group, Inc., Boston, MA, USA.
Maryaline CatillonAnalysis Group, Inc., Boston, MA, USA.
Chunyi XuAnalysis Group, Inc., Boston, MA, USA.
Kirthana SarathyAnalysis Group, Inc., Boston, MA, USA.
Mei Sheng DuhAnalysis Group, Inc., Boston, MA, USA.
Caroline R BaumalApellis Pharmaceuticals, Waltham, MA, USA.
Varun ChaudharyDepartment of Surgery, McMaster University, Hamilton, ON, Canada.ORCID https://orcid.org/0000-0002-9988-4146

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anchored matching-adjusted indirect comparisonavacincaptad pegolefficacygeographic atrophyintravitreal pegcetacoplanmeta-analyses

Identifiers

PMID41112493
PMCPMC12534827

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.