ArticleJTCVS techniques2025
Donation-after-circulatory-death lungs narrow the survival gap between single- and bilateral-lung transplants: A propensity-matched analysis.
Article in JTCVS techniques, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Single-lung transplantation (SLT) traditionally has inferior survival compared with bilateral-lung transplantation (BLT), raising concerns regarding its use. However, with the advent of donation after circulatory death (DCD), contemporary outcomes warrant reassessment. This study evaluates survival outcomes after SLT and BLT in the modern era, focusing specifically on the impact of DCD. Methods: We conducted a retrospective cohort analysis of adult lung transplants performed from 2018 to 2024 using the United Network for Organ Sharing database. Propensity score matching was applied to balance recipient and donor characteristics between SLT and BLT cohorts, followed by Kaplan-Meier and multivariable Cox regression analyses. Results: Among 17,802 lung transplants (3747 SLT and 14,055 BLT), propensity matching yielded 3528 matched pairs. SLT recipients had significantly inferior long-term survival compared with BLT (adjusted hazard ratio [aHR], 1.35; 95% confidence interval [CI], 1.22-1.51; Conclusions: Although BLT is generally associated with superior survival outcomes compared with SLT, our contemporary analysis found that DCD SLT outcomes were comparable with DCD BLT and more favorable than donation after brain death SLT. These findings suggest that DCD lungs may be a viable option for single lung transplantation and highlight the potential role of DCD in expanding the donor pool. Further research is warranted to better understand long-term outcomes and optimize recipient selection for DCD SLT.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.